Many are confusing CBG with CBD, thinking they are referring to the same cannabinoid. But CBG is one of the new players in the growing CBD landscape. Although it shares some similarities with CBD, CBG has its own qualities that set it apart from the other cannabinoids we know.
This post contains useful information about CBG that will help you understand its potential benefits as well as how it works within the human body. Now, without further ado, let’s get to meet the mother of all cannabinoids, CBG.
Known Potential Benefits of CBG
CBG, like CBD, can produce desirable effects on the human body. However, some medical experts say that more robust research regarding CBG’s mechanism of action is needed to confirm the cannabinoid’s potential health benefits.
CBG may help with anxiety and depression:
CBG, like CBD, has been of interest to many individuals seeking natural remedies for anxiety and depression. A small-scale study noted that a significant number of people using cannabis high in CBG reported doing so to alleviate anxiety, with a notable percentage using it for depression as well. The perceived effectiveness of CBG for these conditions compared to conventional medications was also highlighted in the study.
CBG may help with inflammatory bowel disease.
Inflammatory bowel disease (IBD), including conditions like Crohn’s disease and ulcerative colitis, presents challenges such as pain and appetite loss for many patients. Some individuals with IBD turn to cannabis and cannabinoids, including CBG, to alleviate symptoms such as pain and to stimulate appetite.
CBG may help with chronic pain:
Chronic pain affects a substantial portion of the population, and CBG has emerged as a potential alternative or complementary option for pain management. A particular study found that a significant percentage of users preferred CBG over traditional medicines for chronic pain relief.
CBG may help with a healthier brain:
In 2015, researchers from the Department of Biochemistry and Molecular Biology at Complutense University of Madrid conducted a study on mice that demonstrated that CBG could significantly reduce nerve cell damage and inflammation. These effects are primarily attributed to CBG’s antioxidant properties.
Antioxidants help neutralize harmful free radicals in the body, which can damage cells and contribute to inflammation and oxidative stress. Both inflammation and oxidative stress are major factors in the development and progression of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
CBG? Did You Mean CBD?
Yes, we are referring to CBG which is a naturally-occurring cannabinoid in hemp and cannabis plants. It has an interesting nickname which is “mother of all cannabinoids.” This nickname stems from the fact that other cannabinoids, such as cannabidiol (CBD) and tetrahydrocannabinol (THC), are derived from cannabigerolic acid (CBGA), the acidic precursor to CBG.
In the hemp plant, CBGA undergoes enzymatic reactions that convert it into various other cannabinoids, including THC and CBD. As a result, CBG itself is usually present in much smaller quantities compared to these more well-known cannabinoids. This limited presence makes CBG-derived consumer products relatively rare and often more expensive.
Despite its scarcity, CBG is gaining popularity due to its potential health benefits. Research into CBG is still in its early stages, but preliminary findings suggest that it may offer a range of therapeutic properties, including anti-inflammatory, antibacterial, and neuroprotective effects. These potential benefits are driving increased interest and demand for CBG products, even though they are more challenging to produce.
CBG and the Human Body
CBG (Cannabigerol) interacts with the body through a complex network known as the endocannabinoid system (ECS). The ECS is a crucial regulatory system that helps maintain homeostasis, or balance, in the body, ensuring optimal functioning regardless of external conditions.
Mimicking Endocannabinoids
CBG mimics the body’s natural endocannabinoids, which are compounds that the body naturally produces to interact with the ECS. Unlike THC (Tetrahydrocannabinol), CBG does not have psychotropic effects, meaning it won’t produce a high. This makes it an attractive option for those seeking therapeutic benefits without the mind-altering effects associated with THC.
The Role of CB1 and CB2 Receptors
The ECS consists of two primary types of cannabinoid receptors: CB1 and CB2. CB1 receptors are predominantly found in the brain and nervous system, playing a significant role in regulating functions such as mood, memory, and pain perception. CB2 receptors, on the other hand, are primarily located in the immune system and peripheral tissues, where they influence inflammation and immune responses.
CBG works by binding to both CB1 and CB2 receptors. This dual interaction allows CBG to exert a broad range of effects on both the central nervous system and the immune system.
Enhancing Anandamide Function
One of the critical ways CBG influences the ECS is by enhancing the function of anandamide, a neurotransmitter often referred to as the “bliss molecule.” Anandamide is involved in regulating several physiological processes, including pleasure, motivation, appetite, sleep, and pain management.
By binding to the cannabinoid receptors, CBG is believed to inhibit the breakdown of anandamide, thereby increasing its levels and prolonging its positive effects. This can lead to enhanced mood, better sleep, improved appetite regulation, and reduced pain and inflammation.
How to Use CBG
Cannabigerol (CBG) is available in various forms, allowing users to choose the method that best suits their needs and preferences. Here are the different ways to use CBG:
CBG Gummies
CBG gummies are a popular and convenient way to consume CBG. These edibles are infused with a specific dose of CBG, making it easy to monitor your intake. Gummies are discreet, portable, and come in various flavors, which can make them an enjoyable option for those who may not like the taste of CBG oil or other forms.
Pros: Easy to dose, discreet, tasty.
Cons: Slower onset of effects due to digestion, may contain sugar or other additives.
CBG Oil
CBG oil, also known as CBG tincture, is one of the most versatile forms of CBG. It is typically administered sublingually (under the tongue), where it is absorbed directly into the bloodstream, providing faster effects than edibles. CBG oil can also be added to food or beverages for easier consumption.
Pros: Fast absorption, versatile use, precise dosing.
Cons: Some may not like the taste, less convenient on the go.
CBG Topicals
CBG topicals include creams, balms, and lotions infused with CBG. These products are applied directly to the skin, allowing the CBG to interact with local cannabinoid receptors. Topicals are ideal for targeting specific areas of pain, inflammation, or skin conditions without affecting the whole body.
Pros: Targeted relief, non-psychoactive, easy to use.
Cons: Effects may be limited to the area of application, and slower onset compared to other methods.
CBG Capsules
CBG capsules are pre-measured doses of CBG encapsulated in a convenient pill form. They offer a straightforward way to consume CBG, similar to taking a daily supplement. Capsules ensure consistent dosing and are easy to incorporate into your routine.
Pros: Precise dosing, easy to take, no taste.
Cons: Slower onset of effects due to digestion, less flexible dosing.
CBG Vape
CBG vape products allow for the inhalation of CBG through a vaporizer or vape pen. This method provides rapid absorption through the lungs, leading to a quicker onset of effects. Vaping CBG can be more efficient for those needing immediate relief.
Pros: Fast-acting, high bioavailability, convenient.
Cons: Shorter duration of effects, potential respiratory irritation, requires vape equipment.
CBG Isolate
CBG isolate is the purest form of CBG, often available as a powder. It contains 99% pure CBG, with all other plant compounds removed. Isolate can be used in various ways, including adding it to foods, beverages, or other products, making it highly versatile.
Pros: Pure CBG, no taste or odor, versatile use.
Cons: Lack of entourage effect (synergy with other cannabinoids), requires measuring.
How to Dose CBG
When it comes to dosing CBG (Cannabigerol), there isn’t a one-size-fits-all approach. However, some general guidelines can help you find the right dosage for your needs.
Starting with CBG
To begin using CBG, a common recommendation is to start with a daily dose of 5-15 mg. Another rule of thumb is to take 2 mg per 10 lbs of body weight. For example, if you weigh 150 lbs, you might start with a dose of 30 mg per day. If this initial dose feels appropriate, you can gradually increase it, potentially up to 100 mg per day, depending on your needs and how your body responds.
Factors Influencing CBG Dosage
Several factors can influence the ideal CBG dosage for an individual:
Age: Older adults may require different dosages than younger individuals.
Baseline Health: Your overall health and any underlying medical conditions can affect how you respond to CBG.
Underlying Conditions: Specific health issues might require tailored dosages.
Cannabis Experience: Your experience with cannabis products, including tolerance levels, plays a role in determining the right dose.
Finding Your Ideal Dose
Determining your ideal CBG dosage involves a personal trial-and-error process. The key principle is to “start low and go slow,” similar to the approach with CBD. Begin with a low dose and gradually increase it until you achieve the desired effects without experiencing adverse side effects.
| Weight (pounds) | Beginner dosage (mg) | Intermediate dosage (mg) | High dosage (mg) |
| 80 | 16 | 32 | 48 |
| 90 | 18 | 36 | 54 |
| 100 | 20 | 40 | 60 |
| 110 | 22 | 44 | 66 |
| 120 | 24 | 48 | 72 |
| 130 | 26 | 52 | 78 |
| 140 | 28 | 56 | 84 |
| 150 | 30 | 60 | 90 |
| 160 | 32 | 64 | 96 |
| 170 | 34 | 68 | 102 |
| 180 | 36 | 72 | 108 |
| 190 | 38 | 76 | 114 |
| 200 | 40 | 80 | 120 |
| 210 | 42 | 84 | 126 |
| 220 | 44 | 88 | 132 |
| 230 | 46 | 92 | 138 |
| 240 | 48 | 96 | 144 |
| 250 | 50 | 100 | 150 |
Product Labeling and Dosing
Most CBG products are labeled with the amount of CBG in milligrams (mg) or as a percentage of the total product. If this information is not listed, check the lab results provided on the brand’s website. It’s essential to follow the product’s recommended dose, starting on the lower end of the spectrum and gradually building up.
Gradual Introduction
Introducing CBG gradually into your system helps your body adjust to the compound and minimizes the risk of adverse side effects. This method also allows you to monitor how CBG affects you and make informed decisions about increasing your dosage.
CBG vs CBD
Cannabigerol (CBG) and Cannabidiol (CBD) are two prominent cannabinoids found in the cannabis plant. While they share some similarities, they also have distinct differences in their origins, effects, and uses. Here’s a detailed comparison to help you understand how CBG and CBD differ:
Origin and Chemical Structure
CBG (Cannabigerol):
- Often referred to as the “mother of all cannabinoids,” CBG is the precursor from which other cannabinoids, including THC and CBD, are synthesized.
- Cannabigerolic acid (CBGA) is the acidic form of CBG, which, through enzymatic processes, converts into THCA, CBDA, and CBCA, the precursors to THC, CBD, and CBC, respectively.
CBD (Cannabidiol):
- CBD is directly derived from cannabidiolic acid (CBDA), one of the primary cannabinoids formed from CBGA.
- Unlike CBG, CBD is present in larger quantities in most cannabis strains, making it more readily available for extraction and use.
Psychoactive Properties
CBG:
- CBG is non-psychoactive, meaning it does not produce a high. This makes it appealing for those seeking the therapeutic benefits of cannabis without the mind-altering effects of THC.
CBD:
- Similar to CBG, CBD is also non-psychoactive. It can counteract the psychoactive effects of THC, making it useful for individuals looking to mitigate the high associated with THC use.
Health Benefits and Uses
CBG:
- Neuroprotective: CBG has shown promise in protecting nerve cells and reducing inflammation and oxidative stress, which are factors in neurodegenerative diseases.
- Anti-inflammatory: It can help reduce inflammation, making it potentially beneficial for conditions like inflammatory bowel disease (IBD).
CBD:
- Anti-seizure: CBD is well-known for its anti-seizure properties and is used in treating epilepsy, particularly in drug-resistant cases.
- Anxiety and Depression: CBD has been found to reduce anxiety and improve mood, making it a popular natural remedy for mental health conditions.
- Pain Relief: It has analgesic properties that help alleviate chronic pain.
- Anti-inflammatory: Like CBG, CBD also reduces inflammation and is used in treating conditions such as arthritis and multiple sclerosis.
Legal Status
CBG:
- The legal status of CBG is largely dependent on its source. If derived from hemp (cannabis with less than 0.3% THC), CBG is legal in many regions under the same laws that govern CBD. However, laws can vary widely by jurisdiction.
CBD:
- CBD derived from hemp is legal in many countries, including the United States, under the 2018 Farm Bill, provided it contains less than 0.3% THC. However, CBD laws differ internationally and even among states within the U.S.
Availability and Cost
CBG:
- CBG is typically found in lower concentrations in cannabis plants, which makes it rarer and often more expensive than CBD. This rarity is due to most CBGA converting into other cannabinoids as the plant matures.
CBD:
- CBD is abundant in many cannabis strains, making it more accessible and generally less expensive than CBG. Its widespread availability has led to a larger market with a variety of CBD products.
Safety of CBG
While CBG (Cannabigerol) is generally well-tolerated, some individuals may experience side effects. Understanding these potential side effects is important for anyone considering adding CBG to their wellness routine. Here are some of the most commonly reported side effects:
- Sleepiness
- Dry mouth
- Dry eyes
Frequently Asked Questions
How much CBG can be present in a hemp plant?
CBG is present in hemp plants in much smaller quantities than other cannabinoids. Typically, only about 1% of a cannabis plant’s biomass contains CBG, compared to much higher percentages for CBD and THC. This low concentration means that a large amount of plant material is required to extract a small amount of CBG.
Why is CBG more expensive than other cannabinoids?
The higher cost of CBG compared to other cannabinoids is primarily due to its low concentration in cannabis plants, the need for early harvesting, specialized extraction methods, and the current supply-demand dynamics.
Can CBG make me high?
No, CBG (Cannabigerol) cannot make you high. Unlike THC (Tetrahydrocannabinol), which is the primary psychoactive compound in cannabis, CBG is non-psychoactive.
Where can I buy safe and potent CBG products?
XLR8 Delta is a reputable online store known for selling federally legal CBG-infused products. They provide Certificates of Analysis (COAs) to prove the potency and purity of their products, ensuring quality and safety. XLR8 Delta offers affordable CBG products without compromising on quality, making them a trusted choice for consumers seeking reliable Delta 10 THC options.
References
Survey of Patients Employing Cannabigerol-Predominant Cannabis Preparations: Perceived Medical Effects, Adverse Events, and Withdrawal Symptoms (https://www.liebertpub.com/doi/10.1089/can.2021.0058)
The Use of Cannabinoids in the Treatment of Inflammatory Bowel Disease (IBD): A Review of the Literature (https://www.cureus.com/articles/141323-the-use-of-cannabinoids-in-the-treatment-of-inflammatory-bowel-disease-ibd-a-review-of-the-literature#!/)
Neuroprotective properties of cannabigerol in Huntington’s disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322067/)
